The skeleton is formed from cartilage and bone, two of the strongest and most supportive tissues in the body. Most bones develop using hyaline cartilage structures as their 'models.' These supporting structures are then replaced by bone tissue. Epiphyseal plates persist to provide for longitudinal growth of long bones during childhood and become inactive when they grow older. Bones change in shape in time. This remodeling occurs in response to hormones and mechanical stresses acting on the skeleton.
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